Name | Trimethylsulfoxonium iodide |
Synonyms | trimethyl-sulfoxoniuiodide Trimethyl sulfoxide iodide rimethylsulfoxonium iodide Trimethylsulfoxonium iodide Trimethylsulphoxonium iodide Tri methyl sulfoxonium iodide Sulfoxonium,trimethyl-,iodide Trimethyl(oxo)-sulfanylium iodide sulfonium,trimethyl-,iodide,oxide |
CAS | 1774-47-6 |
EINECS | 217-204-2 |
InChI | InChI=1/C3H9OS.HI/c1-5(2,3)4;/h1-3H3;1H/q+1;/p-1 |
InChIKey | BPLKQGGAXWRFOE-UHFFFAOYSA-M |
Molecular Formula | C3H9IOS |
Molar Mass | 220.07 |
Density | 1.7074 (estimate) |
Melting Point | 208-212 °C (dec.) (lit.) |
Water Solubility | 15 g/L (20 ºC) |
Solubility | H2O: 50mg/mL, clear |
Appearance | White solid |
Color | White to light yellow |
BRN | 3595854 |
PH | pH(50g/l, 25℃) : 4.8~6.0 |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Sensitive | Light Sensitive |
MDL | MFCD00011899 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 2 |
RTECS | WS3585000 |
FLUKA BRAND F CODES | 8 |
TSCA | Yes |
HS Code | 29309070 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Properties | Trimethylsulfoxide iodide is a white to light yellow crystal, soluble in water and dimethyl sulfoxide, slightly soluble in methanol. |
Use | Trimethylsulfoxide iodide is used to synthesize methylene transfer reagents for the preparation of epoxy compounds. It is mainly used to synthesize fluconazole. Strong alkali treatment can generate endonium salt, which can react with the carbonyl group of ketones and aldehydes to form epoxides; it can also preferentially react with the double bonds of α,β-unsaturated esters to generate cyclopropyl ester |